miR-125b develops chemoresistance in Ewing sarcoma/primitive neuroectodermal tumor
نویسندگان
چکیده
منابع مشابه
Ewing sarcoma/primitive neuroectodermal tumor arising in the adrenal gland.
Ewing sarcoma (ES)/primitive neuroectodermal tumor (PNET) is a malignant small round blue cell neoplasm of presumed neuroectodermal origin that affects bones and soft tissue in children and young adults. Nearly 80% of the patients are younger than 20 years. The tumor cells characteristically express CD99 (MIC2 antigen), a glycoprotein localized on cell membrane. The defining feature of ES/PNET ...
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Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET) is a tumor of small round cells arising in skeletal tissues. These tumors rarely arise in the stomach. We present a 31-year-old healthy female patient who was admitted to our surgical ward due to upper gastrointestinal hemorrhage. Upper endoscopy revealed a large ulcerated bleeding mass originating from the lesser curvature. Biopsy reveale...
متن کاملPrimitive Neuroectodermal Tumor/Ewing Sarcoma Presenting with Pulmonary Nodular Lesions
Primitive neuroectodermal tumors (PNETs) and Ewing sarcoma (EWS) belong to the same family of malignant, small, round cell neoplasms of soft tissue or bone origin. EWS-PNETs that arise in the lung parenchyma involvement are extremely rare in adults. A case of a 32-year-old male presenting with chest pain and diffuse pulmonary nodules on chest X-ray and diagnosed with Ewing sarcoma-PNETs will be...
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BACKGROUND Chemotherapy is an important component in the treatment paradigm for breast cancers. However, the resistance of cancer cells to chemotherapeutic agents frequently results in the subsequent recurrence and metastasis. Identification of molecular markers to predict treatment outcome is therefore warranted. The aim of the present study was to evaluate whether expression of circulating mi...
متن کاملEwing Sarcoma/Primitive Neuroectodermal Tumor of the Kidney: Two Unusual Presentations of a Rare Tumor
Only few cases of primary renal Ewing's sarcoma have been reported in the literature to date. We present here two cases of renal ES/PNET with an uncanny presentation. The first case was discovered after the patient presented clinically with irradiating flank pain, mimicking the pain related with kidney stones. The second case had clinical presentation of pulmonary thromboembolism after the pati...
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ژورنال
عنوان ژورنال: Cancer Cell International
سال: 2013
ISSN: 1475-2867
DOI: 10.1186/1475-2867-13-21